方法1：
[DllImport("user32.dll", CharSet = CharSet.Auto, SetLastError = true)] static extern IntPtr SendMessage(IntPtr hWnd, uint Msg, uint wParam, uint lParam); const uint WM_APPCOMMAND = 0x319; const uint APPCOMMAND_VOLUME_MUTE = 0x08;
然后调用：
SendMessage(new WindowInteropHelper(this).Handle, WM_APPCOMMAND, 0x200eb0, APPCOMMAND_VOLUME_MUTE * 0x10000);
方法2：
模拟按键的方式。
定义KeyController类：
public class KeyController { #region bVk参数 常量定义 public const byte vbKeyLButton = 0x1; // 鼠标左键 public const byte vbKeyRButton = 0x2; // 鼠标右键 public const byte vbKeyCancel = 0x3; // CANCEL 键 public const byte vbKeyMButton = 0x4; // 鼠标中键 public const byte vbKeyBack = 0x8; // BACKSPACE 键 public const byte vbKeyTab = 0x9; // TAB 键 public const byte vbKeyClear = 0xC; // CLEAR 键 public const byte vbKeyReturn = 0xD; // ENTER 键 public const byte vbKeyShift = 0x10; // SHIFT 键 public const byte vbKeyControl = 0x11; // CTRL 键 public const byte vbKeyAlt = 18; // Alt 键 (键码18) public const byte vbKeyMenu = 0x12; // MENU 键 public const byte vbKeyPause = 0x13; // PAUSE 键 public const byte vbKeyCapital = 0x14; // CAPS LOCK 键 public const byte vbKeyEscape = 0x1B; // ESC 键 public const byte vbKeySpace = 0x20; // SPACEBAR 键 public const byte vbKeyPageUp = 0x21; // PAGE UP 键 public const byte vbKeyEnd = 0x23; // End 键 public const byte vbKeyHome = 0x24; // HOME 键 public const byte vbKeyLeft = 0x25; // LEFT ARROW 键 public const byte vbKeyUp = 0x26; // UP ARROW 键 public const byte vbKeyRight = 0x27; // RIGHT ARROW 键 public const byte vbKeyDown = 0x28; // DOWN ARROW 键 public const byte vbKeySelect = 0x29; // Select 键 public const byte vbKeyPrint = 0x2A; // PRINT SCREEN 键 public const byte vbKeyExecute = 0x2B; // EXECUTE 键 public const byte vbKeySnapshot = 0x2C; // SNAPSHOT 键 public const byte vbKeyDelete = 0x2E; // Delete 键 public const byte vbKeyHelp = 0x2F; // HELP 键 public const byte vbKeyNumlock = 0x90; // NUM LOCK 键 //常用键 字母键A到Z public const byte vbKeyA = 65; public const byte vbKeyB = 66; public const byte vbKeyC = 67; public const byte vbKeyD = 68; public const byte vbKeyE = 69; public const byte vbKeyF = 70; public const byte vbKeyG = 71; public const byte vbKeyH = 72; public const byte vbKeyI = 73; public const byte vbKeyJ = 74; public const byte vbKeyK = 75; public const byte vbKeyL = 76; public const byte vbKeyM = 77; public const byte vbKeyN = 78; public const byte vbKeyO = 79; public const byte vbKeyP = 80; public const byte vbKeyQ = 81; public const byte vbKeyR = 82; public const byte vbKeyS = 83; public const byte vbKeyT = 84; public const byte vbKeyU = 85; public const byte vbKeyV = 86; public const byte vbKeyW = 87; public const byte vbKeyX = 88; public const byte vbKeyY = 89; public const byte vbKeyZ = 90; //数字键盘0到9 public const byte vbKey0 = 48; // 0 键 public const byte vbKey1 = 49; // 1 键 public const byte vbKey2 = 50; // 2 键 public const byte vbKey3 = 51; // 3 键 public const byte vbKey4 = 52; // 4 键 public const byte vbKey5 = 53; // 5 键 public const byte vbKey6 = 54; // 6 键 public const byte vbKey7 = 55; // 7 键 public const byte vbKey8 = 56; // 8 键 public const byte vbKey9 = 57; // 9 键 public const byte vbKeyNumpad0 = 0x60; //0 键 public const byte vbKeyNumpad1 = 0x61; //1 键 public const byte vbKeyNumpad2 = 0x62; //2 键 public const byte vbKeyNumpad3 = 0x63; //3 键 public const byte vbKeyNumpad4 = 0x64; //4 键 public const byte vbKeyNumpad5 = 0x65; //5 键 public const byte vbKeyNumpad6 = 0x66; //6 键 public const byte vbKeyNumpad7 = 0x67; //7 键 public const byte vbKeyNumpad8 = 0x68; //8 键 public const byte vbKeyNumpad9 = 0x69; //9 键 public const byte vbKeyMultiply = 0x6A; // MULTIPLICATIONSIGN(*)键 public const byte vbKeyAdd = 0x6B; // PLUS SIGN(+) 键 public const byte vbKeySeparator = 0x6C; // ENTER 键 public const byte vbKeySubtract = 0x6D; // MINUS SIGN(-) 键 public const byte vbKeyDecimal = 0x6E; // DECIMAL POINT(.) 键 public const byte vbKeyDivide = 0x6F; // DIVISION SIGN(/) 键 //F1到F12按键 public const byte vbKeyF1 = 0x70; //F1 键 public const byte vbKeyF2 = 0x71; //F2 键 public const byte vbKeyF3 = 0x72; //F3 键 public const byte vbKeyF4 = 0x73; //F4 键 public const byte vbKeyF5 = 0x74; //F5 键 public const byte vbKeyF6 = 0x75; //F6 键 public const byte vbKeyF7 = 0x76; //F7 键 public const byte vbKeyF8 = 0x77; //F8 键 public const byte vbKeyF9 = 0x78; //F9 键 public const byte vbKeyF10 = 0x79; //F10 键 public const byte vbKeyF11 = 0x7A; //F11 键 public const byte vbKeyF12 = 0x7B; //F12 键 #endregion #region 引用win32api方法 /// <summary> /// 导入模拟键盘的方法 /// </summary> /// <param name="bVk" >按键的虚拟键值</param> /// <param name= "bScan" >扫描码，一般不用设置，用0代替就行</param> /// <param name= "dwFlags" >选项标志：0：表示按下，2：表示松开</param> /// <param name= "dwExtraInfo">一般设置为0</param> [DllImport("user32.dll")] public static extern void keybd_event(byte bVk, byte bScan, int dwFlags, int dwExtraInfo); #endregion }
然后模拟按钮：
KeyController.keybd_event(173, 0, 0, 0); Thread.Sleep(50); KeyController.keybd_event(173, 0, 2, 0);