被这个错误折磨了一下午，关键时刻还得靠Google，原因是下载的wxPython是adm64的,安装的Python是32位的,一定要下载相匹配的文件。
There are multiple versions available. The easiest way to try, did you install the correct version for you is to start cmd and type:
1) python
2) import wx
3) import wxversion
4) print wxversion.getInstalled()
if errors happen on steps 1-3 then there is something wrong in your installation and reinstallation should fix it. On the step 4 output you can compare to the ride installation requirements.
试到第二步眼睛陡然一亮发现了“不是有效的 Win32 应用程序”，got it!
>>> import wx
Traceback (most recent call last):
File "<stdin>", line 1, in <module>
File "C:Python27libsite-packageswx-2.8-msw-unicodewx\__init__.py", line 4
5, in <module>
from wx._core import *
File "C:Python27libsite-packageswx-2.8-msw-unicodewx\_core.py", line 4, i
n <module>
import _core_
ImportError: DLL load failed: %1 不是有效的 Win32 应用程序。
重新下载wxPython:wxPython2.8-win32-unicode-2.8.12.1-py27.exe
http://sourceforge.net/projects/wxpython/files/wxPython/2.8.12.1/