近日在调试Matlba GUI程序时，因为不想退出程序后手动Clear All来清理，又需要在过程中对WorkSpace进行清理，否则会引用之前的结果导致错误，找了很多资料，国内的论坛什么的都说用Clear，Clear All这种，根本不行，会报错，因为过程中Clear将会导致定义的handles丢失，最后在Matlab的官方论坛中找到了答案：
Clear Global Workspace from GUI Pushbutton
"global (main)workspace" I assume/guess you refer to the baseworkspace.
Try something like
evalin('base','clearvars *' )
or
evalin('base', 'clear variables' )
in the callback function of the pushbutton. See the documentation on clearvars and on clear
说明是，必须加载在一个按钮的Callback中。
感谢参考：https://www.mathworks.com/matlabcentral/answers/79174-clear-global-workspace-from-gui-pushbutton