引自：http://guangboo.org/2013/01/17/solution-link-errorcannot-open-file-python27_dlib
感谢原作者
使用C调用Python函数或解释器时，在添加了Include Directories和Library Directories等配置后，仍然编译错误："LINK : fatal error LNK1104: cannot open file 'python27_d.lib'".代码如下：
#include <stdio.h> #include <Python.h> int main(void) { Py_Initialize(); if(!Py_IsInitialized()){ printf("Python Initialize failed. "); return 1; } PyRun_SimpleString("print('hello world!')"); Py_Finalize(); system("pause"); return 0; }
Stackoverflow贴出了pyconfig.h头文件中对Python27_d.lib的引用（http://stackoverflow.com/questions/11311877/creating-a-dll-from-a-wrapped-cpp-file-with-
swig/14372472#14372472），该文件用于调试用，如下代码：
/* For Windows the Python core is in a DLL by default. Test Py_NO_ENABLE_SHARED to find out. Also support MS_NO_COREDLL for b/w compat */ #if !defined(MS_NO_COREDLL) && !defined(Py_NO_ENABLE_SHARED) # define Py_ENABLE_SHARED 1 /* standard symbol for shared library */ # define MS_COREDLL /* deprecated old symbol */ #endif /* !MS_NO_COREDLL && ... */ /* All windows compilers that use this header support __declspec */ #define HAVE_DECLSPEC_DLL /* For an MSVC DLL, we can nominate the .lib files used by extensions */ #ifdef MS_COREDLL # ifndef Py_BUILD_CORE /* not building the core - must be an ext */ # if defined(_MSC_VER) /* So MSVC users need not specify the .lib file in their Makefile (other compilers are generally taken care of by distutils.) */ # ifdef _DEBUG # pragma comment(lib,"python27_d.lib") # else # pragma comment(lib,"python27.lib") # endif /* _DEBUG */ # endif /* _MSC_VER */ # endif /* Py_BUILD_CORE */ #endif /* MS_COREDLL */
可以发现，只有MS_NO_COREDLL或Py_NO_ENABLE_SHARED被定义了，那么#ifdef MS_COREDLL块的代码就不会被编译。因此可以在Configuration Properties->C/C++->Preprocessor->Preprocessor Definitions添加MS_NO_COREDLL或Py_NO_ENABLE_SHARED，去掉_DEBUG，将没有效果。也可以在引用python.h头文件前添加#define MS_NO_COREDLL或#define Py_NO_ENABLE_SHARED。